Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 1/20 | 0.39 |
| ▸ | TPH1 | P17752 | 1/20 | 0.37 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.35 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ADH5 | P11766 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019729 | 0.84 | TBXA2R (0.37) | GNRHRTPH1TPH2HRH3MCHR1 | |
| SCHEMBL9019679 | 0.72 | TBXA2R (0.37) | GNRHRHRH3MCHR1LSSMAOB | |
| SCHEMBL9019682 | 0.66 | TBXA2R (0.52) | HRH3PDE2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17916879 | 0.66 | HRH3 (0.68) | HRH3MCHR1LSSPDE2AALDH1A1 | |
| SCHEMBL255498 | 0.65 | MAOB (0.62) | MAOBHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3139773 | 0.61 | GRIA2 (0.58) | CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6994229 | 0.60 | TSHR (0.47) | MAOBADH5CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6998233 | 0.60 | TSHR (0.53) | ADH5CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL12310548 | 0.60 | CYP3A4 (0.59) | MAOBHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19850982 | 0.59 | PDE2A (0.55) | HRH3LSSPDE2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496237-B1 | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept[b]indole | PHARMACIA SPA (IT) | 1996-02-14 | — | — | EP | claimed |
| EP-0496237-B1 | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept[b]indole | PHARMACIA SPA (IT) | 1996-02-14 | — | — | EP | disclosed |