Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 6/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.35 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019729 | 0.89 | TBXA2R (0.37) | TBXA2RHRH3GNRHRTBXAS1FFAR1 | |
| SCHEMBL9019683 | 0.83 | TBXA2R (0.51) | TBXA2RHRH3TBXAS1PTGDR | |
| SCHEMBL9019682 | 0.80 | TBXA2R (0.52) | TBXA2RHRH3PTGDR | |
| SCHEMBL9019676 | 0.79 | TBXA2R (0.47) | TBXA2RTBXAS1FFAR1 | |
| SCHEMBL9019678 | 0.77 | TBXA2R (0.42) | TBXA2RHRH3TBXAS1 | |
| SCHEMBL9019726 | 0.75 | TBXA2R (0.52) | TBXA2RTBXAS1 | |
| SCHEMBL9019673 | 0.75 | PTGDR (0.47) | TBXA2RHRH3TBXAS1FFAR1PTGDR | |
| SCHEMBL9019713 | 0.74 | TBXA2R (0.53) | TBXA2RTBXAS1PTGDR | |
| SCHEMBL9019727 | 0.73 | TBXA2R (0.43) | TBXA2RHRH3GNRHRFFAR1PTGDR | |
| SCHEMBL9019725 | 0.72 | GNRHR (0.39) | HRH3GNRHRLSSMAOBMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496237-B1 | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept[b]indole | PHARMACIA SPA (IT) | 1996-02-14 | — | — | EP | claimed |
| EP-0496237-B1 | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept[b]indole | PHARMACIA SPA (IT) | 1996-02-14 | — | — | EP | disclosed |
| US-5238953-A | Thromboxane a2 antagonist | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-08-24 | — | — | US | disclosed |
| EP-0496237-A2 | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept[b]indole | PHARMACIA S.p.A. (IT) | 1992-07-29 | — | — | EP | disclosed |