Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9472330 | 0.82 | TSHR (0.49) | CA1CA2CA7CYP3A4MAPT | |
| SCHEMBL11258229 | 0.81 | ALDH1A1 (0.37) | SMN1; SMN2LMNATDP1ALDH1A1TSHR | |
| SCHEMBL9472291 | 0.81 | TSHR (0.55) | CYP3A4MAPTLMNATDP1ALDH1A1 | |
| SCHEMBL11754279 | 0.81 | USP2 (0.40) | CA1CA2CA7USP2CYP3A4 | |
| SCHEMBL1830477 | 0.79 | TDP1 (0.41) | CA1CA2CA7USP2CYP3A4 | |
| SCHEMBL10956519 | 0.79 | TDP1 (0.41) | CA1CA2CA7USP2CYP3A4 | |
| SCHEMBL8610698 | 0.79 | — | — | |
| SCHEMBL9575322 | 0.79 | CA1 (0.46) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL9019745 | 0.78 | ALDH1A1 (0.47) | LMNATDP1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL16001973 | 0.78 | CA1 (0.42) | CA1CA2CA7SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452680-B1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AG (DE) | 1996-11-06 | — | — | EP | disclosed |
| EP-0448006-B1 | Process for the preparation of acylales | HOECHST AG (DE) | 1995-01-25 | — | — | EP | disclosed |
| US-5231221-A | PROCESS FOR THE PREPARATION OF ACYLALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-27 | — | — | US | disclosed |
| US-5225590-A | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0452680-A1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-23 | — | — | EP | disclosed |
| EP-0448006-A2 | Process for the preparation of acylales | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-25 | — | — | EP | disclosed |
| EP-0187297-B1 | ALKOXY METHYL ETHER AND ALKOXY METHYL ESTER DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1991-08-21 | — | — | EP | disclosed |
| EP-0187297-A2 | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-07-16 | — | — | EP | disclosed |