Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13613723 | 0.85 | DUT (0.36) | DUTFKBP1ATOP2A | |
| SCHEMBL5676651 | 0.82 | PDK2 (0.37) | DUTFKBP1ATOP2A | |
| SCHEMBL22029081 | 0.82 | PDK2 (0.37) | DUTFKBP1ATOP2A | |
| SCHEMBL5676774 | 0.82 | PDK2 (0.37) | DUTFKBP1ATOP2A | |
| SCHEMBL1576228 | 0.78 | DUT (0.34) | DUTFKBP1ATOP2A | |
| SCHEMBL3742158 | 0.77 | DUT (0.34) | DUTFKBP1ATOP2A | |
| SCHEMBL211191 | 0.77 | DUT (0.34) | DUTFKBP1ATOP2A | |
| SCHEMBL24795959 | 0.76 | PDK2 (0.41) | DUTFKBP1A | |
| SCHEMBL1401084 | 0.76 | PDK2 (0.41) | DUTFKBP1A | |
| SCHEMBL21389332 | 0.76 | DUT (0.33) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449191-B1 | 2-(Substituted pyrrolidinylthio)carbapenem derivatives | BANYU PHARMA CO LTD (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5438054-A | Antibacterial agent | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-01 | — | — | US | disclosed |
| US-5374720-A | A thienamycins bactericides has nontoxic, side effect reduction against the kidney and central nervous system | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-12-20 | — | — | US | disclosed |
| WO-1991014687-A1 | 2-(SUBSTITUTED PYRROLIDINYLTHIO)CARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-03 | — | — | WO | disclosed |
| EP-0449191-A1 | 2-(Substituted pyrrolidinylthio)carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |