SCHEMBL9020168

SCHEMBL9020168

OCCN1CCn2nccc21

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TOP2A P11388 1/20 0.36
TOP2B Q02880 1/20 0.36
DPP4 P27487 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9020622 0.81 DPP4 (0.34) DPP4
SCHEMBL8832756 0.77 DPP4 (0.31) DPP4
SCHEMBL9019991 0.70 POLB (0.38) DPP4
SCHEMBL9020671 0.70
SCHEMBL18939001 0.67 F10 (0.41)
SCHEMBL18952188 0.66 CYP19A1 (0.34)
SCHEMBL9020228 0.63 HDAC4 (0.34)
SCHEMBL8833295 0.62
SCHEMBL8832754 0.62
SCHEMBL5148608 0.62 DPP4 (0.31) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0332156-B1 Cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO (JP) 1996-12-18 EP disclosed
US-5366970-A Cephem compounds and pharmaceutically acceptable salts thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-11-22 US disclosed
US-5173485-A Bactericides, microbiocides FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1992-12-22 US disclosed
EP-0332156-A2 Cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-09-13 EP disclosed