SCHEMBL9019991

SCHEMBL9019991

COC(=O)CN1CCn2nccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
KMT2A Q03164 3/20 0.35
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 1/20 0.35
TSHR P16473 1/20 0.35
HSD17B10 Q99714 2/20 0.34
KAT2B Q92831 1/20 0.34
NPC1 O15118 1/20 0.34
AOC3 Q16853 2/20 0.34
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
DPP4 P27487 1/20 0.33
NOTUM Q6P988 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9020139 0.85 GSK3A (0.40) GAAALDH1A1SMN1; SMN2KMT2ALMNA
SCHEMBL2524679 0.69 DRD2 (0.47)
SCHEMBL9020622 0.67 DPP4 (0.34) DPP4
SCHEMBL9299670 0.65 KDM4E (0.42) GAAALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL5859165 0.65 NOTUM (0.59) POLBGAAALDH1A1KDM4EKMT2A
SCHEMBL24127303 0.64 DRD2 (0.33)
SCHEMBL29535160 0.64 SMN1; SMN2 (0.43) GAAALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL9020671 0.63
SCHEMBL5152728 0.63 TSHR (0.42) GAAALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL10913751 0.63 KMT2A (0.54) POLBKDM4ESMN1; SMN2KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0332156-B1 Cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO (JP) 1996-12-18 EP disclosed
US-5366970-A Cephem compounds and pharmaceutically acceptable salts thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-11-22 US disclosed
US-5173485-A Bactericides, microbiocides FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1992-12-22 US disclosed
EP-0332156-A2 Cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-09-13 EP disclosed