Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.40 |
| ▸ | DPP4 | P27487 | 5/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.33 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22248848 | 0.89 | CA2 (0.42) | DPP7DPP4DPP8DPP9CA2 | |
| SCHEMBL14850861 | 0.89 | CA2 (0.42) | DPP7DPP4DPP8DPP9CA2 | |
| SCHEMBL20386751 | 0.89 | CA2 (0.42) | DPP7DPP4DPP8DPP9CA2 | |
| SCHEMBL14843027 | 0.78 | DPP7 (0.44) | DPP7DPP4DPP8DPP9 | |
| SCHEMBL14850782 | 0.78 | DPP7 (0.44) | DPP7DPP4DPP8DPP9 | |
| SCHEMBL6820644 | 0.74 | DPP7 (0.56) | DPP7DPP4DPP8DPP9CA2 | |
| SCHEMBL6823435 | 0.74 | DPP7 (0.56) | DPP7DPP4DPP8DPP9CA2 | |
| SCHEMBL16435188 | 0.74 | DPP7 (0.46) | DPP7DPP4DPP8DPP9 | |
| SCHEMBL16435187 | 0.73 | DPP7 (0.59) | DPP7DPP4DPP8DPP9 | |
| SCHEMBL10842135 | 0.73 | CA2 (0.42) | DPP7DPP4CA2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621535-A1 | THIAZOLIDINE LINKER FOR THE CONJUGATION OF DRUGS TO ANTIBODIES | Philogen S.p.A. (IT) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041451-A1 | THIAZOLIDINE LINKER FOR THE CONJUGATION OF DRUGS TO ANTIBODIES | PHILOGEN S.P.A. (IT) | 2012-04-05 | — | — | WO | disclosed |