Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.55 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.49 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.47 |
| ▸ | HRH1 | P35367 | 6/20 | 0.46 |
| ▸ | HRH2 | P25021 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL305857 | 1.00 | CYP3A4 (0.56) | CYP3A4SLC7A5CPB2SLC15A2CPB1 | |
| SCHEMBL1537239 | 0.96 | CPB2 (0.60) | CYP3A4SLC7A5CPB2HRH3HRH4 | |
| SCHEMBL10705310 | 0.91 | CYP3A4 (0.60) | CYP3A4SLC7A5CPB2 | |
| SCHEMBL1537285 | 0.88 | CYP3A4 (0.71) | CYP3A4SLC7A5HRH3HRH4 | |
| SCHEMBL163444 | 0.88 | CYP3A4 (0.71) | CYP3A4SLC7A5HRH3HRH4 | |
| SCHEMBL28413657 | 0.87 | CPB2 (0.50) | CYP3A4SLC7A5CPB2SLC15A2CPB1 | |
| Hydrochloric Acid SCHEMBL28331180 | 0.86 | CYP3A4 (0.69) | CYP3A4SLC7A5HRH3HRH4 | |
| Histidine SCHEMBL27986330 | 0.84 | CYP3A4 (0.76) | CYP3A4SLC7A5CPB2SLC15A2CPB1 | |
| Histidine SCHEMBL28204033 | 0.83 | CYP3A4 (0.74) | CYP3A4SLC7A5CPB2SLC15A2CPB1 | |
| SCHEMBL5712340 | 0.83 | CYP3A4 (0.57) | CYP3A4SLC7A5CPB2HRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9909088-B2 | Method for isomerisation of hop alpha-acids to iso-alpha-acids | IFAST NV (BE) | 2018-03-06 | — | — | US | disclosed |
| EP-2622060-B1 | IMPROVED METHOD FOR ISOMERISATION OF HOP ALPHA-ACIDS TO ISO-ALPHA-ACIDS | IFAST NV (BE) | 2015-05-20 | — | — | EP | disclosed |
| US-20130209653-A1 | METHOD FOR ISOMERISATION OF HOP ALPHA-ACIDS TO ISO-ALPHA-ACIDS | IFAST NV (BE) | 2013-08-15 | — | — | US | disclosed |
| EP-2622060-A1 | IMPROVED METHOD FOR ISOMERISATION OF HOP ALPHA-ACIDS TO ISO-ALPHA-ACIDS | Ifast NV (BE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041994-A1 | IMPROVED METHOD FOR ISOMERISATION OF HOP ALPHA-ACIDS TO ISO-ALPHA-ACIDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2012-04-05 | — | — | WO | disclosed |