Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021198 | 0.84 | ALDH1A1 (0.77) | ALDH1A1CA1CA2MEN1KMT2A | |
| SCHEMBL11106260 | 0.83 | ALDH1A1 (0.63) | ALDH1A1CA1CA2PRMT1TDP1 | |
| SCHEMBL6565074 | 0.82 | ALDH1A1 (0.64) | ALDH1A1CA1CA2PRMT1TDP1 | |
| SCHEMBL9484341 | 0.82 | ALDH1A1 (0.61) | ALDH1A1CA1CA2PRMT1TDP1 | |
| Hydrochloric Acid SCHEMBL6565204 | 0.81 | ALDH1A1 (0.62) | ALDH1A1CA1CA2PRMT1TDP1 | |
| SCHEMBL412302 | 0.81 | ALDH1A1 (0.79) | ALDH1A1CA1CA2PRMT1TDP1 | |
| SCHEMBL14156120 | 0.80 | ALDH1A1 (0.84) | ALDH1A1CA1CA2PRMT1TDP1 | |
| SCHEMBL10460354 | 0.80 | ALDH1A1 (0.70) | ALDH1A1CA1CA2PRMT1TDP1 | |
| SCHEMBL6804085 | 0.80 | PRMT1 (0.88) | ALDH1A1CA1CA2PRMT1TDP1 | |
| SCHEMBL10463090 | 0.80 | ALDH1A1 (0.61) | ALDH1A1CA1CA2PRMT1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |