Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021174 | 0.93 | SLC6A2 (0.67) | SIGMAR1SLC6A4SLC6A3CYP1A2CYP2D6 | |
| SCHEMBL9020983 | 0.86 | SIGMAR1 (0.61) | SIGMAR1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL9022573 | 0.84 | SLC6A4 (0.58) | SIGMAR1SLC6A4SLC6A3CYP1A2CYP2D6 | |
| SCHEMBL10357800 | 0.83 | SIGMAR1 (0.81) | SIGMAR1SLC6A4SLC6A3TP53CYP1A2 | |
| SCHEMBL14198311 | 0.81 | SIGMAR1 (0.64) | SIGMAR1SLC6A4SLC6A3TP53CYP1A2 | |
| SCHEMBL9020789 | 0.81 | SLC6A4 (0.61) | SIGMAR1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL13960252 | 0.80 | KCNA3 (0.65) | SIGMAR1CYP2D6 | |
| SCHEMBL4048093 | 0.79 | SIGMAR1 (0.42) | SIGMAR1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL4048099 | 0.79 | SIGMAR1 (0.42) | SIGMAR1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL9021099 | 0.79 | CYP3A4 (0.66) | SIGMAR1SLC6A4SLC6A3CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470686-B1 | (Benzhydryloxyethylpiperidyl)aliphatic acid derivatives and their use in the treatment of allergies and asthma | SANKYO CO (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5294623-A | (Benzhydryloxyethylpiperidyl) aliphatic acid derivatives and their use in the treatment of allergies and asthma | SANKYO COMPANY, LIMITED (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0470686-A2 | (Benzhydryloxyethylpiperidyl)aliphatic acid derivatives and their use in the treatment of allergies and asthma | Sankyo Company Limited (JP) | 1992-02-12 | — | — | EP | disclosed |