SCHEMBL902141

SCHEMBL902141

C=CC[C@H](O)C(=C)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.39
TET2 Q6N021 3/20 0.38
TET3 O43151 1/20 0.38
TET1 Q8NFU7 1/20 0.38
GRIK1 P39086 2/20 0.36
GRIK2 Q13002 2/20 0.36
CPA1 P15085 1/20 0.35
ABCC4 O15439 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31199 1.00 CYP2C19 (0.39) CYP2C19TET2TET3TET1GRIK1
Vinyl Chloride SCHEMBL4029780 0.94 CYP2C19 (0.36) CYP2C19TET2TET3TET1GRIK1
Methacrylic Acid SCHEMBL11132733 0.92 CYP2C19 (0.35) CYP2C19TET2TET3TET1GRIK1
SCHEMBL731704 0.87 TDP1 (0.43) CYP2C19TET2TET3TET1GRIK1
Vinyl Chloride SCHEMBL5447669 0.80
SCHEMBL362182 0.78 GRIK1 (0.47) CYP2C19TET2TET3TET1GRIK1
SCHEMBL6450262 0.78 THRB (0.38)
SCHEMBL4079703 0.77
SCHEMBL5674658 0.77
SCHEMBL246812 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9428669-B2 Two-part polyurethanes based on hyperbranched polymers SIKA TECHNOLOGY AG (CH) 2016-08-30 US claimed
US-20130210998-A1 TWO-PART POLYURETHANES BASED ON HYPERBRANCHED POLYMERS SIKA TECHNOLOGY AG (CH) 2013-08-15 US claimed
EP-2621989-A1 TWO-PART POLYURETHANES BASED ON HYPERBRANCHED POLYMERS Sika Technology AG (CH) 2013-08-07 EP claimed
WO-2012041951-A1 TWO-PART POLYURETHANES BASED ON HYPERBRANCHED POLYMERS SIKA TECHNOLOGY AG (CH) 2012-04-05 WO claimed
US-6541580-B1 Controlling living polymerization via e.g. polyphosphazene initiators CARNEGIE MELLON UNIVERSITY 2003-04-01 US claimed
EP-0813552-B1 MODIFIED ACRYL COPOLYMER BOLLIG & KEMPER GMBH & CO KG (DE) 1998-12-23 EP claimed
EP-4355835-A1 WATERBORNE COATING COMPOSITION Allnex Netherlands B.V. (NL) 2024-04-24 EP disclosed
WO-2022263402-A1 WATERBORNE COATING COMPOSITION ALLNEX NETHERLANDS B.V. (NL) 2022-12-22 WO disclosed
US-9428669-B2 Two-part polyurethanes based on hyperbranched polymers SIKA TECHNOLOGY AG (CH) 2016-08-30 US disclosed
US-20130210998-A1 TWO-PART POLYURETHANES BASED ON HYPERBRANCHED POLYMERS SIKA TECHNOLOGY AG (CH) 2013-08-15 US disclosed
US-20060258829-A1 Urethane (meth)acrylate resin with acrylic backbone and ink compositions containing the same CYTEC SURFACE SPECIALTIES, S.A. (BE) 2006-11-16 US disclosed
US-6005056-A REACTION PRODUCT OF EPOXY GROUP CONTAINING ACRYLIC COPOLYMERWITH A CARBOXYL GROUP CONTAINING POLYCYCLOALIPHATIC COMPOUND;CLEAR COATS FOR AUTOMOBILES; HIGH GLOSS BOLLIG & KEMPER KG (DE) 1999-12-21 US disclosed
EP-0145267-A2 Method and compositions relating to the activation of fluorescent whitening agents THE DOW CHEMICAL COMPANY (US) 1985-06-19 EP disclosed
US-4128635-A Cosmetic emulsions containing copolymers of alkyl (meth) acrylates and mono- or polyhydroxyalkyl (meth) acrylates HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1978-12-05 US disclosed