Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | GLI1 | P08151 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417061 | 0.82 | NOS2 (0.41) | NOS2NOS3NOS1DPP4MEN1 | |
| SCHEMBL417059 | 0.82 | NOS2 (0.41) | NOS2NOS3NOS1DPP4MEN1 | |
| SCHEMBL417060 | 0.82 | NOS2 (0.41) | NOS2NOS3NOS1DPP4MEN1 | |
| SCHEMBL3113842 | 0.79 | NOS2 (0.42) | NOS2NOS3NOS1DPP4MEN1 | |
| SCHEMBL4458323 | 0.78 | CPN1 (0.41) | NOS2NOS3NOS1DPP4MEN1 | |
| SCHEMBL4458322 | 0.78 | CPN1 (0.41) | NOS2NOS3NOS1DPP4MEN1 | |
| SCHEMBL4458327 | 0.78 | CPN1 (0.41) | NOS2NOS3NOS1DPP4MEN1 | |
| SCHEMBL801077 | 0.77 | NOS2 (0.43) | NOS2NOS3NOS1DPP4MEN1 | |
| SCHEMBL14443285 | 0.77 | NOS2 (0.43) | NOS2NOS3NOS1DPP4MEN1 | |
| SCHEMBL800667 | 0.77 | NOS2 (0.43) | NOS2NOS3NOS1DPP4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8003132-A | — | — | None | — | — | JP | disclosed |
| JP-H083132-A | PROLYLPROLINE DERIVATIVE AND ITS NEW PRODUCTION | JAPAN TOBACCO INC | 1996-01-09 | — | — | JP | disclosed |