SCHEMBL9022274

SCHEMBL9022274

CC(C)(NC(=O)C1CC[C@H]2[C@@H]3CC=C4NC(=O)CC[C@]4(C)[C@@H]3CC[C@]12C)c1cccs1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 12/20 0.49
SRD5A1 P18405 6/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9022269 1.00 SRD5A2 (0.49) SRD5A2SRD5A1
SCHEMBL9022346 0.86 SRD5A2 (0.60) SRD5A2SRD5A1
SCHEMBL9022357 0.86 SRD5A2 (0.60) SRD5A2SRD5A1
SCHEMBL9022728 0.86 SRD5A1 (0.44) SRD5A2SRD5A1
SCHEMBL6432037 0.85 SRD5A2 (0.66) SRD5A2SRD5A1
SCHEMBL6545719 0.85 SRD5A2 (0.66) SRD5A2SRD5A1
SCHEMBL9022253 0.84 SRD5A2 (0.49) SRD5A2SRD5A1
SCHEMBL9022259 0.84 SRD5A2 (0.49) SRD5A2SRD5A1
SCHEMBL9022217 0.83 SRD5A2 (0.60) SRD5A2SRD5A1
SCHEMBL9022210 0.83 SRD5A2 (0.60) SRD5A2SRD5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0484094-B1 Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use SANKYO CO (JP) 1996-06-26 EP claimed
US-5302621-A Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use SANKYO COMPANY, LIMITED (JP) 1994-04-12 US claimed
EP-0484094-A2 Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use Sankyo Company Limited (JP) 1992-05-06 EP claimed
EP-0484094-B1 Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use SANKYO CO (JP) 1996-06-26 EP disclosed
US-5302621-A Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use SANKYO COMPANY, LIMITED (JP) 1994-04-12 US disclosed
EP-0484094-A2 Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use Sankyo Company Limited (JP) 1992-05-06 EP disclosed