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Sugi Predict / Compounds / SCHEMBL9022693

SCHEMBL9022693

SCHEMBL9022693

CN1C(=O)CC[C@]2(C)[C@H]3CC[C@]4(C)[C@@H](OC(=O)NC(c5ccccc5)c5ccc(O)cc5)CC[C@H]4[C@@H]3CC[C@@H]12

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ SRD5A1 P18405 4/20 0.52
▸ SRD5A2 P31213 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9022361 0.86 SRD5A2 (0.56) SRD5A1SRD5A2
SCHEMBL9022353 0.86 SRD5A2 (0.56) SRD5A1SRD5A2
SCHEMBL9022405 0.85 AR (0.53) SRD5A2
SCHEMBL9022401 0.85 SRD5A1 (0.52) SRD5A1SRD5A2
SCHEMBL9022517 0.83 SRD5A2 (0.54) SRD5A1SRD5A2
SCHEMBL9022102 0.82 SRD5A1 (0.49) SRD5A1SRD5A2
SCHEMBL9022937 0.81 SRD5A2 (0.49) SRD5A1SRD5A2
SCHEMBL9023109 0.81 SRD5A2 (0.60) SRD5A1SRD5A2
SCHEMBL9023101 0.81 SRD5A2 (0.60) SRD5A1SRD5A2
SCHEMBL7751215 0.81 SRD5A1 (0.56) SRD5A1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0484094-B1 Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use SANKYO CO (JP) 1996-06-26 — — EP claimed