Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 8/20 | 0.49 |
| ▸ | SRD5A1 | P18405 | 5/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9022734 | 0.96 | SRD5A2 (0.53) | SRD5A2SRD5A1CYP2C19CYP19A1NR1I2 | |
| SCHEMBL9022100 | 0.87 | SRD5A1 (0.48) | SRD5A2SRD5A1CYP2C19CYP19A1NR1I2 | |
| SCHEMBL9022607 | 0.87 | SRD5A2 (0.64) | SRD5A2SRD5A1 | |
| SCHEMBL9022615 | 0.87 | SRD5A2 (0.64) | SRD5A2SRD5A1 | |
| SCHEMBL9022611 | 0.86 | SRD5A1 (0.48) | SRD5A2SRD5A1CYP2C19CYP19A1NR1I2 | |
| SCHEMBL9022428 | 0.85 | SRD5A2 (0.48) | SRD5A2SRD5A1CYP2C19CYP19A1NR1I2 | |
| SCHEMBL9022566 | 0.83 | SRD5A1 (0.46) | SRD5A2SRD5A1CYP2C19CYP19A1NR1I2 | |
| SCHEMBL9022293 | 0.82 | SRD5A2 (0.68) | SRD5A2SRD5A1 | |
| SCHEMBL9022292 | 0.82 | SRD5A2 (0.68) | SRD5A2SRD5A1 | |
| SCHEMBL9022693 | 0.81 | SRD5A1 (0.52) | SRD5A2SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0484094-B1 | Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use | SANKYO CO (JP) | 1996-06-26 | — | — | EP | claimed |