Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 4/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.37 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.37 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.37 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.37 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.37 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9022708 | 1.00 | GNAI3 (0.39) | GNAI3GNAO1GNAI1HRH1IKBKB | |
| Hydrochloric Acid SCHEMBL9014127 | 0.99 | GNAI3 (0.41) | GNAI3GNAO1GNAI1HRH1IKBKB | |
| Fumaric Acid SCHEMBL9014073 | 0.91 | HRH1 (0.48) | GNAI3GNAO1GNAI1HRH1HRH3 | |
| Fumaric Acid SCHEMBL9014088 | 0.91 | HRH1 (0.48) | GNAI3GNAO1GNAI1HRH1HRH3 | |
| SCHEMBL9022785 | 0.81 | HRH1 (0.46) | GNAI3GNAO1GNAI1HRH1IKBKB | |
| SCHEMBL9022816 | 0.81 | HRH1 (0.46) | GNAI3GNAO1GNAI1HRH1IKBKB | |
| SCHEMBL9023043 | 0.81 | HRH1 (0.46) | GNAI3GNAO1GNAI1HRH1IKBKB | |
| Hydrochloric Acid SCHEMBL9013864 | 0.80 | HRH3 (0.48) | GNAI3GNAO1GNAI1HRH3 | |
| SCHEMBL8800057 | 0.80 | HRH1 (0.47) | GNAI3GNAO1GNAI1HRH1IKBKB | |
| SCHEMBL9014079 | 0.79 | HRH3 (0.43) | HRH3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449195-B1 | Aminobenzene compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-08 | — | — | EP | claimed |
| EP-0449195-A2 | Aminobenzene compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-02 | — | — | EP | claimed |
| EP-0449195-B1 | Aminobenzene compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-08 | — | — | EP | disclosed |