Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CTSC | P53634 | 6/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4966557 | 0.79 | CYP2C19 (0.57) | CYP2C19TAAR1RAB9ACTSCADRA2A | |
| SCHEMBL24017115 | 0.79 | CYP2C19 (0.55) | CYP2C19TAAR1RAB9ACTSCADRA2A | |
| SCHEMBL657170 | 0.79 | CYP2C19 (0.55) | CYP2C19TAAR1RAB9ACTSCADRA2A | |
| SCHEMBL24017051 | 0.79 | CYP2C19 (0.55) | CYP2C19TAAR1RAB9ACTSCADRA2A | |
| SCHEMBL30846601 | 0.78 | EPHX1 (0.48) | TAAR1CTSC | |
| SCHEMBL30846613 | 0.78 | EPHX1 (0.48) | TAAR1CTSC | |
| SCHEMBL3289195 | 0.78 | EPHX1 (0.48) | TAAR1CTSC | |
| SCHEMBL4971797 | 0.78 | CYP2C19 (0.52) | CYP2C19TAAR1CTSC | |
| Hydrochloric Acid SCHEMBL9482622 | 0.77 | EPHX1 (0.47) | TAAR1CTSC | |
| SCHEMBL5796511 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0484094-B1 | Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use | SANKYO CO (JP) | 1996-06-26 | — | — | EP | disclosed |
| US-5302621-A | Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use | SANKYO COMPANY, LIMITED (JP) | 1994-04-12 | — | — | US | disclosed |
| EP-0484094-A2 | Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use | Sankyo Company Limited (JP) | 1992-05-06 | — | — | EP | disclosed |