Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CTSC | P53634 | 8/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1425381 | 0.87 | CYP2C19 (0.48) | CYP2C19TAAR1RAB9ACTSCADRA2A | |
| SCHEMBL14860743 | 0.87 | CYP2C19 (0.53) | CYP2C19TAAR1RAB9ACTSCADRA2A | |
| SCHEMBL12262584 | 0.87 | CYP2C19 (0.48) | CYP2C19TAAR1RAB9ACTSCADRA2A | |
| SCHEMBL12262043 | 0.87 | CYP2C19 (0.48) | CYP2C19TAAR1RAB9ACTSCADRA2A | |
| SCHEMBL24017115 | 0.86 | CYP2C19 (0.55) | CYP2C19TAAR1RAB9ACTSCADRA2A | |
| SCHEMBL24017051 | 0.86 | CYP2C19 (0.55) | CYP2C19TAAR1RAB9ACTSCADRA2A | |
| SCHEMBL9874276 | 0.86 | TAAR1 (0.53) | CYP2C19TAAR1RAB9ACTSCADRA2A | |
| SCHEMBL4668703 | 0.84 | CYP2C19 (0.50) | CYP2C19TAAR1RAB9ACTSCADRA2A | |
| SCHEMBL9326082 | 0.84 | CYP2C19 (0.46) | CYP2C19TAAR1RAB9ACTSCADRA2A | |
| SCHEMBL2753684 | 0.82 | CYP2C19 (0.44) | CYP2C19TAAR1RAB9ACTSCADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867202-B1 | METHOD FOR PRODUCING STEREOSELECTIVE EPOXYKETONE COMPOUND | NISSAN CHEMICAL IND LTD (JP) | 2017-08-09 | — | — | EP | disclosed |
| US-9187442-B2 | Method for producing stereoselective epoxyketone compound | NISSAN CHEMICAL INDUSTIES, LTD. (JP) | 2015-11-17 | — | — | US | disclosed |
| US-20150126755-A1 | METHOD FOR PRODUCING STEREOSELECTIVE EPOXYKETONE COMPOUND | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-05-07 | — | — | US | disclosed |
| EP-2867202-A2 | METHOD FOR PRODUCING STEREOSELECTIVE EPOXYKETONE COMPOUND | Nissan Chemical Industries, Ltd. (JP) | 2015-05-06 | — | — | EP | disclosed |
| US-9018403-B2 | Method for producing tetrahydropyran compound and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-04-28 | — | — | US | disclosed |
| US-20140256921-A1 | METHOD FOR PRODUCING TETRAHYDROPYRAN COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-09-11 | — | — | US | disclosed |
| US-8765974-B2 | Method for producing tetrahydropyran compound and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-07-01 | — | — | US | disclosed |
| EP-2420504-B1 | METHOD FOR PRODUCING TETRAHYDROPYRAN COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2014-01-15 | — | — | EP | disclosed |
| WO-2014003203-A2 | METHOD FOR PRODUCING STEREOSELECTIVE EPOXYKETONE COMPOUND | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-01-03 | — | — | WO | disclosed |
| US-20120046476-A1 | METHOD FOR PRODUCING TETRAHYDROPYRAN COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-02-23 | — | — | US | disclosed |
| EP-2420504-A1 | METHOD FOR PRODUCING TETRAHYDROPYRAN COMPOUND AND INTERMEDIATE THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2012-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256921-A1 | METHOD FOR PRODUCING TETRAHYDROPYRAN COMPOUND AND INTERMEDIATE THEREOF | CYP3A5, CYP2E1, CYP3A43 | CYP2C19 33/4885TAAR1 1048/4885RAB9A 1061/4885 |
| US-20150126755-A1 | METHOD FOR PRODUCING STEREOSELECTIVE EPOXYKETONE COMPOUND | HSD17B7, CYP51A1, AKR1B10 | CYP2C19 521/4885TAAR1 1580/4885RAB9A 1633/4885 |
| US-20120046476-A1 | METHOD FOR PRODUCING TETRAHYDROPYRAN COMPOUND AND INTERMEDIATE THEREOF | HPD, CYP3A5, CYP2E1 | CYP2C19 36/4885TAAR1 1050/4885RAB9A 804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.