Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | HBB | P68871 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | PNP | P00491 | 7/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | EDNRA | P25101 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | HPRT1 | P00492 | 5/20 | 0.56 |
| ▸ | POLG | P54098 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | VCP | P55072 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9027295 | 0.99 | HBB (0.64) | MEN1KMT2AHBBMAPK1PNP | |
| Hydrochloric Acid SCHEMBL9027278 | 0.99 | HBB (0.64) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL7496272 | 0.93 | MEN1 (0.68) | MEN1KMT2AHBBMAPK1PNP | |
| Hydrochloric Acid SCHEMBL4908550 | 0.92 | HBB (0.69) | MEN1KMT2AHBBMAPK1PNP | |
| Hydrochloric Acid SCHEMBL9275315 | 0.91 | HBB (0.68) | MEN1KMT2AHBBMAPK1PNP | |
| Hydrochloric Acid SCHEMBL9414134 | 0.91 | HBB (0.68) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL16581549 | 0.86 | MEN1 (0.68) | MEN1KMT2AHBBMAPK1PNP | |
| Valine SCHEMBL16581547 | 0.82 | MEN1 (0.81) | MEN1KMT2AHBBMAPK1PNP | |
| Acyclovir SCHEMBL5806934 | 0.81 | MEN1 (0.77) | MEN1KMT2AHBBMAPK1PNP | |
| Hydrochloric Acid SCHEMBL9023678 | 0.80 | HBB (0.84) | MEN1KMT2AHBBMAPK1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596542-B1 | Therapeutic nucleosides | WELLCOME FOUND (GB) | 1996-05-29 | — | — | EP | claimed |
| US-5061708-A | TREATMENT OF INFECTION BY HERPES OR CYTOMEGALO VIRUS | BURROUGHS WELLCOME CO. (US) | 1991-10-29 | — | — | US | claimed |