Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023182 | 1.00 | LTB4R (0.79) | LTB4RLTB4R2 | |
| SCHEMBL9022627 | 0.97 | LTB4R (0.84) | LTB4RLTB4R2 | |
| SCHEMBL9022634 | 0.97 | LTB4R (0.84) | LTB4RLTB4R2 | |
| SCHEMBL9023229 | 0.97 | LTB4R (0.84) | LTB4RLTB4R2 | |
| SCHEMBL9524838 | 0.95 | LTB4R (0.78) | LTB4RLTB4R2 | |
| SCHEMBL9023527 | 0.93 | LTB4R (0.92) | LTB4RLTB4R2 | |
| SCHEMBL9023529 | 0.93 | LTB4R (0.92) | LTB4RLTB4R2 | |
| SCHEMBL9022858 | 0.90 | LTB4R (0.73) | LTB4RLTB4R2 | |
| SCHEMBL9022862 | 0.90 | LTB4R (0.73) | LTB4RLTB4R2 | |
| SCHEMBL9023315 | 0.90 | LTB4R (0.73) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548250-B1 | SUBSTITUTED BICYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY | RHONE POULENC RORER INT (US) | 1996-03-27 | — | — | EP | disclosed |
| US-5468898-A | Substituted naphthylene compounds exhibiting selective leukotriene B4 antagonist activity | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1995-11-21 | — | — | US | disclosed |
| EP-0548250-A4 | SUBSTITUTED BICYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B 4? ANTAGONIST ACTIVITY | — | 1993-10-27 | — | — | EP | disclosed |
| EP-0548250-A1 | SUBSTITUTED BICYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B 4? ANTAGONIST ACTIVITY. | RHONE POULENC RORER INT (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992004321-A1 | SUBSTITUTED BICYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-03-19 | — | — | WO | disclosed |