SCHEMBL9023263

SCHEMBL9023263

CN(C)/N=[C]\c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
GRM5 P41594 2/20 0.36
TSHR P16473 4/20 0.36
LMNA P02545 3/20 0.33
CYP3A4 P08684 2/20 0.33
PYCR1 P32322 2/20 0.33
USP2 O75604 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
ALDH1A1 P00352 3/20 0.32
BLM P54132 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NPC1 O15118 1/20 0.32
MTOR P42345 1/20 0.32
RAB9A P51151 1/20 0.32
KCNN4 O15554 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9023268 1.00 APP (0.39) APPNPSR1GRM5TSHRLMNA
SCHEMBL10514789 0.71 MIF (0.44) TSHRLMNACYP3A4PYCR1USP2
SCHEMBL1133440 0.70
SCHEMBL1133439 0.70
SCHEMBL354449 0.65
SCHEMBL27565692 0.65
SCHEMBL6351767 0.65
SCHEMBL497768 0.65 TSHR (0.48) APPNPSR1GRM5TSHRLMNA
SCHEMBL354450 0.65
SCHEMBL4191846 0.65 APP (0.39) APPGRM5TSHRLMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0665225-B1 4-Phenethylamino pyrimidine derivative, process for preparing the same and agricultural and horticultural chemical for controlling noxious organisms containing the same UBE INDUSTRIES (JP) 1996-11-27 EP claimed
US-5498612-A INSECTICIDE, ACARICIDE, FUNGICIDE, NEMATOCIDE UBE INDUSTRIES, LTD. (JP) 1996-03-12 US claimed
EP-0665225-A1 4-Phenethylamino pyrimidine derivative, process for preparing the same and agricultural and horticultural chemical for controlling noxious organisms containing the same UBE INDUSTRIES, LTD. (JP) 1995-08-02 EP claimed
EP-0470665-B1 1-Hydroxyindole fungicides EASTMAN KODAK CO (US) 1996-04-24 EP disclosed
US-5118695-A 1-HYDROXYINDOLE FUNGICIDES EASTMAN KODAK COMPANY (US) 1992-06-02 US disclosed
EP-0470665-A1 1-Hydroxyindole fungicides EASTMAN KODAK COMPANY (US) 1992-02-12 EP disclosed