Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6359014 | 1.00 | APP (0.39) | APPCA4TSHRHTR2AGRM5 | |
| SCHEMBL5415934 | 1.00 | APP (0.39) | APPCA4TSHRHTR2AGRM5 | |
| SCHEMBL14480036 | 0.78 | ALDH1A1 (0.42) | GRM5NPC1RAB9ACA12CA1 | |
| SCHEMBL14480035 | 0.78 | ALDH1A1 (0.42) | GRM5NPC1RAB9ACA12CA1 | |
| SCHEMBL17217098 | 0.78 | ALDH1A1 (0.42) | GRM5NPC1RAB9ACA12CA1 | |
| SCHEMBL14480042 | 0.76 | LMNA (0.36) | GRM5KCNH2LMNA | |
| SCHEMBL17219426 | 0.76 | CA1 (0.50) | APPCA4NPC1RAB9ACA12 | |
| SCHEMBL14480022 | 0.76 | LMNA (0.36) | GRM5KCNH2LMNA | |
| SCHEMBL14480013 | 0.76 | ACHE (0.35) | GRM5KDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL14480031 | 0.76 | GSK3B (0.37) | RAB9AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293674-A1 | Azinyl Imidazoazine and Azinyl Carboxamide | BAYER CROPSCIENCE AG (DE) | 2008-11-27 | — | — | US | claimed |
| EP-0665225-B1 | 4-Phenethylamino pyrimidine derivative, process for preparing the same and agricultural and horticultural chemical for controlling noxious organisms containing the same | UBE INDUSTRIES (JP) | 1996-11-27 | — | — | EP | claimed |
| US-5498612-A | INSECTICIDE, ACARICIDE, FUNGICIDE, NEMATOCIDE | UBE INDUSTRIES, LTD. (JP) | 1996-03-12 | — | — | US | claimed |
| EP-0665225-A1 | 4-Phenethylamino pyrimidine derivative, process for preparing the same and agricultural and horticultural chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1995-08-02 | — | — | EP | claimed |
| EP-2940012-B1 | TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF | SUMITOMO CHEMICAL CO (JP) | 2019-01-30 | — | — | EP | disclosed |
| US-9560850-B2 | Tetrazolinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-07 | — | — | US | disclosed |
| US-20150336908-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-11-26 | — | — | US | disclosed |
| EP-2940012-A1 | TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF | Sumitomo Chemical Company Limited (JP) | 2015-11-04 | — | — | EP | disclosed |
| US-7473669-B2 | Substituted 4,5-dihydro-1,2,4-triazin-6-ones, 1,2,4-triazin-6-ones, and their use as fungicides | DOW AGROSCIENCES LLC (US) | 2009-01-06 | — | — | US | disclosed |
| US-20080293674-A1 | Azinyl Imidazoazine and Azinyl Carboxamide | BAYER CROPSCIENCE AG (DE) | 2008-11-27 | — | — | US | disclosed |
| CN-100415725-C | Pyrimidine compound and application thereof | SUMITOMO CHEMICAL CO (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-101189214-A | Substituted 4, 5-dihydro-1, 2, 4-triazin-6-ones, 1, 2, 4-triazin-6-ones and their use as fungicides | DOW AGROSCIENCES LLC (US) | 2008-05-28 | — | — | CN | disclosed |
| CN-1120333-A | Imino-substituted phenylacetamides, their preparation and fungicides containing them | BASF AG (DE) | 1996-04-10 | — | — | CN | disclosed |
| US-4798890-A | SULFONATION OF A DITHIOAZETIDINONE | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1989-01-17 | — | — | US | disclosed |
| US-4740596-A | Process for preparation of 4-sulfonylthio azetidinone derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1988-04-26 | — | — | US | disclosed |
| US-4713452-A | Process for preparation of azetidinone derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1987-12-15 | — | — | US | disclosed |
| EP-0034924-B1 | PROCESS FOR PREPARING 3-IODOMETHYL CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1984-07-04 | — | — | EP | disclosed |
| EP-0034924-A2 | Process for preparing 3-iodomethyl cephalosporins | ELI LILLY AND COMPANY (US) | 1981-09-02 | — | — | EP | disclosed |
| US-4266049-A | Process for 3-iodomethyl cephalosporins | ELI LILLY AND COMPANY (US) | 1981-05-05 | — | — | US | disclosed |
| EP-0018674-A1 | Benzodioxincarboxylic acid derivatives, their preparation and their inclusion in lipogenesis inhibiting compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-11-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293674-A1 | Azinyl Imidazoazine and Azinyl Carboxamide | AZI2, NISCH, ZYX | APP 4590/4885CA4 461/4885TSHR 3493/4885 |
| US-20150336908-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | RTN3, CYP51A1, TCOF1 | APP 3709/4885CA4 2893/4885TSHR 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.