Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 9/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TOP2A | P11388 | 6/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023293 | 0.90 | KMT2A (0.51) | TOP1KCNH2KMT2AKDM4EALDH1A1 | |
| SCHEMBL10914315 | 0.88 | TOP1 (0.42) | TOP1KCNH2KMT2AKDM4EALDH1A1 | |
| SCHEMBL9023061 | 0.87 | TOP1 (0.38) | TOP1KCNH2KMT2AKDM4EALDH1A1 | |
| SCHEMBL10442795 | 0.86 | KMT2A (0.56) | TOP1KMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL10911437 | 0.84 | KMT2A (0.42) | TOP1KMT2AKDM4EALDH1A1TOP2A | |
| SCHEMBL10911087 | 0.84 | TOP1 (0.47) | TOP1KCNH2KMT2AKDM4EALDH1A1 | |
| SCHEMBL9022897 | 0.84 | KCNH2 (0.54) | TOP1KCNH2KDM4EALDH1A1TOP2A | |
| SCHEMBL10911362 | 0.84 | KMT2A (0.41) | TOP1KCNH2KMT2AKDM4EALDH1A1 | |
| SCHEMBL10913415 | 0.82 | KDM4E (0.56) | TOP1KCNH2KMT2AKDM4EALDH1A1 | |
| SCHEMBL10914229 | 0.81 | KDM4E (0.52) | TOP1KMT2AKDM4EALDH1A1TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500835-B1 | A NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVE | DAE WOONG PHARMA (KR) | 1996-12-27 | — | — | EP | claimed |