Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TOP1 | P11387 | 3/20 | 0.48 |
| ▸ | TOP2A | P11388 | 9/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.47 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023391 | 0.90 | TOP1 (0.42) | KMT2ATOP1TOP2AKCNH2TOP2B | |
| SCHEMBL9022786 | 0.88 | KMT2A (0.46) | KMT2ATOP1TOP2AKCNH2TOP2B | |
| SCHEMBL9870128 | 0.88 | KMT2A (0.51) | KMT2ATOP1TOP2AKCNH2TOP2B | |
| SCHEMBL9665137 | 0.87 | KMT2A (0.53) | KMT2ATOP1TOP2ATOP2BEPHA2 | |
| SCHEMBL9022525 | 0.86 | KMT2A (0.47) | KMT2ATOP1TOP2AKCNH2TOP2B | |
| SCHEMBL30626277 | 0.86 | KDM4E (0.58) | KMT2ATOP1TOP2ATOP2BEPHA2 | |
| SCHEMBL29080644 | 0.86 | KDM4E (0.58) | KMT2ATOP1TOP2ATOP2BEPHA2 | |
| SCHEMBL9869658 | 0.85 | KMT2A (0.69) | KMT2ATOP1TOP2ATOP2BALDH1A1 | |
| SCHEMBL9869272 | 0.84 | TOP1 (0.54) | KMT2ATOP1TOP2AKCNH2TOP2B | |
| SCHEMBL9870457 | 0.84 | KMT2A (0.53) | KMT2ATOP1TOP2ATOP2BEPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500835-B1 | A NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVE | DAE WOONG PHARMA (KR) | 1996-12-27 | — | — | EP | claimed |
| EP-0500835-B1 | A NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVE | DAE WOONG PHARMA (KR) | 1996-12-27 | — | — | EP | disclosed |
| EP-0500835-A1 | A NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVE. | DAE WOONG PHARMA (KR) | 1992-09-02 | — | — | EP | disclosed |
| WO-1992004342-A1 | A NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVE | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1992-03-19 | — | — | WO | disclosed |