Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B14 | Q9BPX1 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746411 | 0.84 | CNR2 (0.47) | HSD17B14LMNAKDM4EALDH1A1GAA | |
| SCHEMBL9023714 | 0.78 | IRAK4 (0.47) | LMNAHTTKDM4EALDH1A1TP53 | |
| SCHEMBL9339006 | 0.75 | MAPT (0.44) | LMNAHTTKDM4EALDH1A1TP53 | |
| SCHEMBL9335203 | 0.71 | UNG (0.40) | HSD17B14HTTKDM4EALDH1A1MAPT | |
| SCHEMBL19070659 | 0.71 | F2 (0.56) | LMNAKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL18463775 | 0.71 | KDM4E (0.39) | HSD17B14LMNAKDM4EMAPTAR | |
| SCHEMBL9335094 | 0.70 | BACE1 (0.36) | HSD17B14HTTKDM4EGAAMAPT | |
| SCHEMBL25167088 | 0.70 | NPC1 (0.41) | CDK5CDK5R1KDM1APARP1MEN1 | |
| SCHEMBL9757049 | 0.68 | NR4A2 (0.41) | HSD17B14LMNAKDM4EALDH1A1GAA | |
| SCHEMBL16396188 | 0.66 | PBRM1 (0.59) | LMNAKDM4EALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725063-A1 | Quinoline derivatives | CIBA-GEIGY AG (CH) | 1996-08-07 | — | — | EP | disclosed |