Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 9/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GRN | P28799 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11509018 | 0.91 | PTPRB (0.47) | PTPRBPTPN1PTPN2PTPRATHRA | |
| SCHEMBL11646444 | 0.85 | PTPRB (0.44) | PTPRBPTPN1PTPN2PTPRAELANE | |
| SCHEMBL3665931 | 0.84 | ESR1 (0.53) | PTPRBPTPN1PTPN2PTPRAELANE | |
| SCHEMBL14290217 | 0.84 | ALDH1A1 (0.45) | PTPRBPTPN1PTPN2PTPRAMMP8 | |
| SCHEMBL15059305 | 0.84 | EPHX2 (0.44) | PTPRBPTPN1PTPN2PTPRABLM | |
| SCHEMBL11530777 | 0.84 | HPGD (0.45) | PTPRBPTPN1PTPN2PTPRAMMP8 | |
| SCHEMBL6469058 | 0.82 | GRN (0.50) | PTPRBALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13903099 | 0.82 | PTPRB (0.54) | PTPRBALDH1A1CA1CA2 | |
| SCHEMBL4768519 | 0.82 | KMT2A (0.45) | PTPRBPTPN1PTPN2PTPRAMMP8 | |
| SCHEMBL18999227 | 0.82 | CA1 (0.51) | PTPN1ALDH1A1CYP2C19CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699668-A1 | 1-(2-BENZIMIDAZOLYL)-1,5-DIAZACYCLOOCTANE DERIVATIVE | Kissei Pharmaceutical Co., Ltd. (JP) | 1996-03-06 | — | — | EP | disclosed |