Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9023223 | 0.99 | LSS (0.46) | LSSITGB3ITGA2BCHRM1MMP2 | |
| SCHEMBL9024381 | 0.90 | ITGB3 (0.47) | LSSITGB3ITGA2BCHRM1MMP2 | |
| Hydrochloric Acid SCHEMBL9023730 | 0.90 | ITGB3 (0.55) | LSSITGB3ITGA2BCHRM1MMP2 | |
| Hydrochloric Acid SCHEMBL9024801 | 0.89 | ITGB3 (0.46) | LSSITGB3ITGA2BCHRM1MMP2 | |
| SCHEMBL9023517 | 0.88 | ITGB3 (0.48) | LSSITGB3ITGA2BCHRM1MMP2 | |
| SCHEMBL9023769 | 0.88 | LSS (0.43) | LSSITGB3ITGA2BCHRM1MMP2 | |
| Hydrochloric Acid SCHEMBL9023867 | 0.84 | ITGB3 (0.53) | LSSITGB3ITGA2BCHRM1KMT2A | |
| SCHEMBL9023827 | 0.82 | LSS (0.48) | LSSITGB3ITGA2BKMT2AMAPT | |
| Hydrochloric Acid SCHEMBL9023920 | 0.81 | ITGB3 (0.48) | LSSITGB3ITGA2BCHRM1MMP2 | |
| SCHEMBL9023476 | 0.81 | ITGB3 (0.44) | LSSITGB3ITGA2BCHRM1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718287-A2 | Piperazine derivatives, medicaments containing them, their use, and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1996-06-26 | — | — | EP | disclosed |