Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 7/20 | 0.85 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lerisetron SCHEMBL30669539 | 0.92 | HTR3A (1.00) | HTR3ASOS1 | |
| Lerisetron SCHEMBL141124 | 0.92 | HTR3A (1.00) | HTR3ASOS1 | |
| SCHEMBL8879490 | 0.91 | HTR3A (0.71) | HTR3ASOS1 | |
| Lerisetron SCHEMBL29040939 | 0.91 | HTR3A (0.97) | HTR3ASOS1 | |
| SCHEMBL8881095 | 0.90 | HTR3A (0.86) | HTR3ASOS1 | |
| SCHEMBL7341277 | 0.89 | HTR3A (0.75) | HTR3A | |
| SCHEMBL7623108 | 0.88 | HTR3A (0.91) | HTR3ASOS1 | |
| SCHEMBL7168715 | 0.87 | HTR3A (0.81) | HTR3A | |
| SCHEMBL7431298 | 0.82 | HTR3A (1.00) | HTR3ASOS1 | |
| SCHEMBL20715423 | 0.81 | CYP2D6 (0.66) | HTR3ASOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699668-A1 | 1-(2-BENZIMIDAZOLYL)-1,5-DIAZACYCLOOCTANE DERIVATIVE | Kissei Pharmaceutical Co., Ltd. (JP) | 1996-03-06 | — | — | EP | disclosed |