Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9141658 | 1.00 | LTB4R (0.85) | LTB4RLTB4R2 | |
| SCHEMBL9023229 | 0.92 | LTB4R (0.84) | LTB4RLTB4R2 | |
| SCHEMBL9022634 | 0.92 | LTB4R (0.84) | LTB4RLTB4R2 | |
| SCHEMBL9022627 | 0.92 | LTB4R (0.84) | LTB4RLTB4R2 | |
| SCHEMBL6759616 | 0.92 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL6759618 | 0.92 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL9023316 | 0.91 | LTB4R (0.88) | LTB4RLTB4R2 | |
| SCHEMBL9140103 | 0.91 | LTB4R (0.81) | LTB4RLTB4R2 | |
| SCHEMBL9524838 | 0.90 | LTB4R (0.78) | LTB4RLTB4R2 | |
| SCHEMBL9524451 | 0.90 | LTB4R (0.92) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548250-B1 | SUBSTITUTED BICYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY | RHONE POULENC RORER INT (US) | 1996-03-27 | — | — | EP | disclosed |
| US-5468898-A | Substituted naphthylene compounds exhibiting selective leukotriene B4 antagonist activity | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1995-11-21 | — | — | US | disclosed |