SCHEMBL9024159

SCHEMBL9024159

COC1(OCC(=O)O)C=C[CH]C=C1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2320901 0.61 PAM (0.32)
SCHEMBL5075375 0.60
Methoxyacetic Acid SCHEMBL23045145 0.59 POLB (0.46) POLBSMN1; SMN2
Methoxyacetic Acid SCHEMBL48842 0.58
Methoxymethane SCHEMBL3826793 0.56 TSHR (0.45) POLBSMN1; SMN2
Methoxyacetic Acid SCHEMBL2770038 0.56
Methoxyacetic Acid SCHEMBL2771714 0.56
Methoxyacetic Acid SCHEMBL5069102 0.56
Methoxyacetic Acid SCHEMBL570981 0.56
Methoxyacetic Acid SCHEMBL5072152 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0398179-B1 Rhodanine derivatives and pharmaceutical compositions NISSHIN FLOUR MILLING CO (JP) 1996-01-17 EP disclosed
US-5116855-A Aldose reductase inhibitors; antidiabetic agents NISSHIN FLOUR MILLING CO., LTD. (JP) 1992-05-26 US disclosed
EP-0398179-A1 Rhodanine derivatives and pharmaceutical compositions NISSHIN FLOUR MILLING CO., LTD. (JP) 1990-11-22 EP disclosed