Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024281 | 1.00 | NAMPT (0.48) | NAMPTHTTMAPTMEN1KMT2A | |
| SCHEMBL8538118 | 0.96 | NAMPT (0.52) | NAMPTHTTMAPTMEN1KMT2A | |
| SCHEMBL8538119 | 0.96 | NAMPT (0.52) | NAMPTHTTMAPTMEN1KMT2A | |
| SCHEMBL8539011 | 0.84 | NAMPT (0.54) | NAMPTHTTMAPTMEN1KMT2A | |
| SCHEMBL8539008 | 0.84 | NAMPT (0.54) | NAMPTHTTMAPTMEN1KMT2A | |
| SCHEMBL16760194 | 0.78 | LTA4H (0.50) | HTTMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8541054 | 0.74 | MEN1 (0.51) | HTTMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8541057 | 0.74 | MEN1 (0.51) | HTTMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL348856 | 0.74 | CHRNA7 (0.57) | L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL4848969 | 0.74 | NAMPT (0.58) | NAMPTHTTMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715627-A1 | INDOLE DERIVATIVES AS THROMBOXANE A2 ANTAGONISTS | Pfizer Limited (GB) | 1996-06-12 | — | — | EP | disclosed |