Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11873738 | 0.83 | CARM1 (0.46) | TSHRCARM1PRMT6PRMT8SMN1; SMN2 | |
| SCHEMBL616042 | 0.81 | TSHR (0.62) | TSHRCARM1PRMT6PRMT8SMN1; SMN2 | |
| SCHEMBL27376496 | 0.80 | TSHR (0.51) | TSHRCARM1PRMT6PRMT8SMN1; SMN2 | |
| SCHEMBL19715501 | 0.79 | TSHR (0.61) | TSHRCARM1PRMT6PRMT8SMN1; SMN2 | |
| SCHEMBL17398952 | 0.78 | TSHR (0.68) | TSHRCARM1PRMT6PRMT8SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL19715538 | 0.78 | TSHR (0.59) | TSHRCARM1PRMT6PRMT8SMN1; SMN2 | |
| SCHEMBL17193571 | 0.78 | TSHR (0.59) | TSHRCARM1PRMT6PRMT8SMN1; SMN2 | |
| SCHEMBL9302526 | 0.78 | CARM1 (0.68) | TSHRCARM1PRMT6PRMT8SMN1; SMN2 | |
| SCHEMBL9760037 | 0.78 | TSHR (0.56) | TSHRCARM1PRMT6PRMT8SMN1; SMN2 | |
| SCHEMBL615516 | 0.77 | TSHR (0.65) | TSHRCARM1PRMT6PRMT8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491243-B1 | Alkylaminoalkylamino and -ether compounds as well as processes and intermediates for their preparation, and medicaments containing these compounds | KALI CHEMIE PHARMA GMBH (DE) | 1996-05-15 | — | — | EP | disclosed |
| US-5212173-A | Gastrointestinal | KALI-CHEMIE PHARMA GMBH (DE) | 1993-05-18 | — | — | US | disclosed |
| EP-0491243-A1 | Alkylaminoalkylamino and -ether compounds as well as processes and intermediates for their preparation, and medicaments containing these compounds | Kali-Chemie Pharma GmbH (DE) | 1992-06-24 | — | — | EP | disclosed |