Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.56 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.56 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | HTR1B | P28222 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17398952 | 0.96 | TSHR (0.68) | TSHRCARM1PRMT6PRMT8SMN1; SMN2 | |
| SCHEMBL19715501 | 0.87 | TSHR (0.61) | TSHRCARM1PRMT6PRMT8SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL19715538 | 0.86 | TSHR (0.59) | TSHRCARM1PRMT6PRMT8SMN1; SMN2 | |
| SCHEMBL11978894 | 0.83 | ALDH1A1 (0.47) | TSHRGAAALDH1A1ACHE | |
| SCHEMBL9302526 | 0.82 | CARM1 (0.68) | TSHRCARM1PRMT6PRMT8SMN1; SMN2 | |
| SCHEMBL14376704 | 0.82 | PYCR1 (0.49) | TSHRHTR1DHTR1BALDH1A1 | |
| SCHEMBL17193571 | 0.82 | TSHR (0.59) | TSHRCARM1PRMT6PRMT8SMN1; SMN2 | |
| SCHEMBL9760037 | 0.82 | TSHR (0.56) | TSHRCARM1PRMT6PRMT8SMN1; SMN2 | |
| SCHEMBL615516 | 0.81 | TSHR (0.65) | TSHRCARM1PRMT6PRMT8SMN1; SMN2 | |
| SCHEMBL7919445 | 0.81 | TSHR (0.58) | TSHRCARM1PRMT6PRMT8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466287-B2 | Process for producing tricyclic ketone | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2013-06-18 | — | — | US | disclosed |
| US-20120041204-A1 | PROCESS FOR PRODUCING TRICYCLIC KETONE | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2012-02-16 | — | — | US | disclosed |
| US-8067595-B2 | Process for producing tricyclic ketone | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2011-11-29 | — | — | US | disclosed |
| US-20090023927-A1 | Process for producing tricyclic ketone | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2009-01-22 | — | — | US | disclosed |
| EP-1900740-A1 | PROCESS FOR PRODUCING TRICYCLIC KETONE | Kabushiki Kaisha Yakult Honsha (JP) | 2008-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041204-A1 | PROCESS FOR PRODUCING TRICYCLIC KETONE | TKT, DCK, COASY | TSHR 3783/4885CARM1 2193/4885PRMT6 3463/4885 |
| US-20090023927-A1 | Process for producing tricyclic ketone | TKT, DCK, COASY | TSHR 3783/4885CARM1 2193/4885PRMT6 3463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.