Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 19/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902570 | 0.85 | DGAT1 (0.44) | DGAT1ADORA2AKCNH2SOAT1 | |
| SCHEMBL902484 | 0.83 | DGAT1 (0.64) | DGAT1ADORA2AKCNH2SOAT1 | |
| SCHEMBL902152 | 0.79 | DGAT1 (0.67) | DGAT1ADORA2AKCNH2SOAT1 | |
| SCHEMBL902382 | 0.79 | DGAT1 (0.72) | DGAT1ADORA2AKCNH2SOAT1 | |
| SCHEMBL16661339 | 0.78 | DGAT1 (0.60) | DGAT1ADORA2AKCNH2SOAT1 | |
| SCHEMBL10189192 | 0.78 | DGAT1 (0.65) | DGAT1ADORA2AKCNH2SOAT1 | |
| SCHEMBL901149 | 0.77 | DGAT1 (0.77) | DGAT1ADORA2AKCNH2SOAT1 | |
| SCHEMBL10147219 | 0.77 | DGAT1 (0.60) | DGAT1ADORA2AKCNH2 | |
| SCHEMBL902756 | 0.76 | DGAT1 (0.72) | DGAT1ADORA2AKCNH2SOAT1 | |
| SCHEMBL902755 | 0.76 | DGAT1 (0.70) | DGAT1ADORA2AKCNH2SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044567-A2 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |