Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 7/20 | 0.44 |
| ▸ | F3 | P13726 | 7/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | MME | P08473 | 3/20 | 0.41 |
| ▸ | ACE | P12821 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024510 | 1.00 | GHSR (0.53) | GHSRAGTR1XIAPF7F3 | |
| SCHEMBL7796021 | 0.87 | GHSR (0.53) | GHSRAGTR1XIAPF7F3 | |
| SCHEMBL9105221 | 0.87 | GHSR (0.42) | GHSRAGTR1XIAPF7F3 | |
| SCHEMBL9105226 | 0.87 | GHSR (0.42) | GHSRAGTR1XIAPF7F3 | |
| SCHEMBL7785847 | 0.85 | GHSR (0.51) | GHSRAGTR1XIAPF7F3 | |
| SCHEMBL9222685 | 0.85 | GHSR (0.51) | GHSRAGTR1XIAPF7F3 | |
| SCHEMBL7785912 | 0.85 | GHSR (0.51) | GHSRAGTR1XIAPF7F3 | |
| SCHEMBL9087316 | 0.85 | GHSR (0.58) | GHSRAGTR1XIAPF7F3 | |
| SCHEMBL9089411 | 0.85 | GHSR (0.56) | GHSRAGTR1XIAPF7F3 | |
| SCHEMBL9024310 | 0.85 | GHSR (0.72) | GHSRAGTR1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513974-B1 | Novel benzo-fused lactams that promote the release of growth hormone | MERCK & CO INC (US) | 1996-09-04 | — | — | EP | claimed |
| EP-0513974-A1 | Novel benzo-fused lactams that promote the release of growth hormone | MERCK & CO. INC. (US) | 1992-11-19 | — | — | EP | claimed |
| US-5310737-A | Benzo-fused lactams that promote the release of growth hormone | MERCK & CO., INC. (US) | 1994-05-10 | — | — | US | disclosed |
| US-5206235-A | Animal growth regulators; stimulants | MERCK & CO., INC. (US) | 1993-04-27 | — | — | US | disclosed |