Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 4/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 4/20 | 0.38 |
| ▸ | F3 | P13726 | 4/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 4/20 | 0.37 |
| ▸ | MME | P08473 | 3/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794660 | 0.89 | GHSR (0.56) | XIAPGHSRAGTR1F7F3 | |
| SCHEMBL9024424 | 0.87 | GHSR (0.55) | XIAPGHSRAGTR1 | |
| SCHEMBL9105107 | 0.86 | GHSR (0.42) | XIAPGHSRAGTR1F7F3 | |
| SCHEMBL9105116 | 0.86 | GHSR (0.42) | XIAPGHSRAGTR1F7F3 | |
| SCHEMBL9221689 | 0.86 | XIAP (0.43) | XIAPGHSRAGTR1F7F3 | |
| SCHEMBL7785909 | 0.86 | GHSR (0.48) | XIAPGHSRAGTR1F7F3 | |
| SCHEMBL9181252 | 0.85 | XIAP (0.43) | XIAPGHSRAGTR1F7F3 | |
| SCHEMBL9181269 | 0.85 | XIAP (0.43) | XIAPGHSRAGTR1F7F3 | |
| SCHEMBL8909563 | 0.85 | GHSR (0.45) | XIAPGHSRAGTR1 | |
| SCHEMBL7792142 | 0.85 | GHSR (0.55) | XIAPGHSRAGTR1F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513974-B1 | Novel benzo-fused lactams that promote the release of growth hormone | MERCK & CO INC (US) | 1996-09-04 | — | — | EP | claimed |
| EP-0513974-A1 | Novel benzo-fused lactams that promote the release of growth hormone | MERCK & CO. INC. (US) | 1992-11-19 | — | — | EP | claimed |
| EP-0513974-B1 | Novel benzo-fused lactams that promote the release of growth hormone | MERCK & CO INC (US) | 1996-09-04 | — | — | EP | disclosed |
| US-5310737-A | Benzo-fused lactams that promote the release of growth hormone | MERCK & CO., INC. (US) | 1994-05-10 | — | — | US | disclosed |
| US-5206235-A | Animal growth regulators; stimulants | MERCK & CO., INC. (US) | 1993-04-27 | — | — | US | disclosed |
| EP-0513974-A1 | Novel benzo-fused lactams that promote the release of growth hormone | MERCK & CO. INC. (US) | 1992-11-19 | — | — | EP | disclosed |
| WO-1992016524-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1992-10-01 | — | — | WO | disclosed |