Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023732 | 0.86 | TACR1 (0.61) | TACR1PRKG1 | |
| Oxalic Acid SCHEMBL9024694 | 0.70 | TACR1 (0.62) | TACR1 | |
| Oxalic Acid SCHEMBL9024675 | 0.70 | TACR1 (0.62) | TACR1 | |
| Oxalic Acid SCHEMBL9024687 | 0.70 | TACR1 (0.62) | TACR1 | |
| SCHEMBL9024304 | 0.70 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8138471 | 0.69 | CTSL (0.44) | TACR1PRKG1 | |
| SCHEMBL8137610 | 0.69 | CTSL (0.44) | TACR1PRKG1 | |
| SCHEMBL21359781 | 0.69 | PSEN1 (0.53) | TACR1 | |
| SCHEMBL20995912 | 0.69 | PSEN1 (0.53) | TACR1 | |
| SCHEMBL24335872 | 0.69 | PSEN1 (0.45) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600952-B1 | AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK SHARP & DOHME (GB) | 1996-04-17 | — | — | EP | disclosed |
| US-5459270-A | Tachykinin antagonist for central nervous systum disorders and cardiovascular disorders | MERCK SHARP & DOHME LIMITED (GB) | 1995-10-17 | — | — | US | disclosed |
| EP-0600952-A1 | AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | MERCK SHARP & DOHME (GB) | 1994-06-15 | — | — | EP | disclosed |
| WO-1993004040-A1 | AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK SHARP & DOHME LIMITED (GB) | 1993-03-04 | — | — | WO | disclosed |
| EP-0528495-A1 | Azacyclic compounds, processes for their preparation and pharmaceutical compositions containing them | MERCK SHARP & DOHME LTD. (GB) | 1993-02-24 | — | — | EP | disclosed |