Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 5/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006133 | 1.00 | TBXA2R (0.47) | TBXA2RPTGDRTBXAS1ALDH1A1CYP3A4 | |
| SCHEMBL9006096 | 0.93 | PTGDR (0.47) | TBXA2RPTGDRTBXAS1ALDH1A1MEN1 | |
| SCHEMBL9006089 | 0.93 | PTGDR (0.47) | TBXA2RPTGDRTBXAS1ALDH1A1MEN1 | |
| SCHEMBL9006118 | 0.92 | TBXA2R (0.41) | TBXA2RPTGDRTBXAS1ALDH1A1CYP3A4 | |
| SCHEMBL9024778 | 0.92 | TBXA2R (0.41) | TBXA2RPTGDRTBXAS1ALDH1A1CYP3A4 | |
| SCHEMBL9024635 | 0.92 | PTGDR (0.46) | TBXA2RPTGDRTBXAS1ALDH1A1CA12 | |
| SCHEMBL9006075 | 0.92 | PTGDR (0.46) | TBXA2RPTGDRTBXAS1ALDH1A1CA12 | |
| SCHEMBL9006115 | 0.92 | TBXA2R (0.49) | TBXA2RPTGDR | |
| SCHEMBL9024816 | 0.92 | TBXA2R (0.49) | TBXA2RPTGDR | |
| SCHEMBL9006108 | 0.90 | PTGDR (0.46) | TBXA2RPTGDRTBXAS1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367130-B1 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-10-02 | — | — | EP | disclosed |
| US-5264453-A | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-23 | — | — | US | disclosed |