Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetonitrile SCHEMBL28272236 | 0.90 | HPGD (0.47) | HPGDSMN1; SMN2ABL1TAAR1DRD4 | |
| SCHEMBL30505689 | 0.85 | CYP2C9 (0.50) | HPGDSMN1; SMN2TAAR1CYP2C9NPC1 | |
| SCHEMBL3456460 | 0.85 | HPGD (0.44) | HPGDSMN1; SMN2ABL1TAAR1DRD4 | |
| SCHEMBL7025724 | 0.79 | MEN1 (0.49) | HPGDSMN1; SMN2TAAR1DRD4CYP2C9 | |
| SCHEMBL28468257 | 0.79 | MEN1 (0.46) | HPGDSMN1; SMN2TAAR1DRD4DRD3 | |
| SCHEMBL4218262 | 0.78 | TAAR1 (0.47) | HPGDSMN1; SMN2TAAR1DRD4DRD3 | |
| SCHEMBL28226695 | 0.77 | TAAR1 (0.62) | HPGDSMN1; SMN2TAAR1CYP2C9TSHR | |
| SCHEMBL9353749 | 0.77 | LMNA (0.41) | HPGDSMN1; SMN2TAAR1CYP2C9NPC1 | |
| SCHEMBL27288253 | 0.77 | TAAR1 (0.39) | HPGDSMN1; SMN2ABL1TAAR1DRD4 | |
| Acetonitrile SCHEMBL28270697 | 0.77 | KDM4E (0.45) | HPGDSMN1; SMN2TAAR1DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924295-A | Furimazine derivative and preparation method and application thereof | 广州博鹭腾生物科技有限公司 | 2024-04-26 | — | — | CN | disclosed |
| EP-0667855-A4 | SUBSTITUTED ARYLALKYNYL- AND HETEROARYLALKYNYL-N-HYDROXYUREA INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS. | ABBOTT LAB (US) | 1996-02-21 | — | — | EP | disclosed |
| EP-0667855-A1 | SUBSTITUTED ARYLALKYNYL- AND HETEROARYLALKYNYL-N-HYDROXYUREA INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994011342-A1 | SUBSTITUTED ARYLALKYNYL- AND HETEROARYLALKYNYL-N-HYDROXYUREA INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1994-05-26 | — | — | WO | disclosed |