Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.58 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.58 |
| ▸ | AHCY | P23526 | 4/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.56 |
| ▸ | PDE4A | P27815 | 3/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.56 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.56 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024927 | 1.00 | PRMT5 (0.58) | PRMT5WDR77AHCYHIF1ATMEM97 | |
| SCHEMBL11518921 | 0.91 | PRMT5 (0.58) | PRMT5WDR77AHCYHIF1ATMEM97 | |
| SCHEMBL6297541 | 0.91 | PRMT5 (0.58) | PRMT5WDR77AHCYHIF1ATMEM97 | |
| SCHEMBL27918251 | 0.82 | PRMT5 (0.64) | PRMT5WDR77AHCYADORA3ADORA2A | |
| SCHEMBL561654 | 0.82 | PRMT5 (0.64) | PRMT5WDR77AHCYADORA3ADORA2A | |
| SCHEMBL561516 | 0.82 | PRMT5 (0.64) | PRMT5WDR77AHCYADORA3ADORA2A | |
| SCHEMBL561515 | 0.82 | PRMT5 (0.64) | PRMT5WDR77AHCYADORA3ADORA2A | |
| SCHEMBL14853754 | 0.81 | PRMT5 (0.65) | PRMT5WDR77AHCYADORA3ADORA2A | |
| SCHEMBL6426564 | 0.81 | PRMT5 (0.65) | PRMT5WDR77AHCYADORA3ADORA2A | |
| SCHEMBL14946260 | 0.81 | PRMT5 (0.65) | PRMT5WDR77AHCYADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515156-B1 | Processes for the diastereo-selective synthesis of nucleosides | IAF BIOCHEM INT (CA) | 1996-02-07 | — | — | EP | disclosed |