Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.30 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024241 | 0.91 | MAPT (0.32) | — | |
| SCHEMBL9023862 | 0.88 | NQO2 (0.36) | ALDH1A1KCNJ5KCNJ3 | |
| SCHEMBL9024634 | 0.86 | MAPT (0.32) | — | |
| SCHEMBL9023350 | 0.85 | TOP2A (0.38) | ALDH1A1 | |
| SCHEMBL9023942 | 0.85 | NQO1 (0.35) | — | |
| SCHEMBL9024021 | 0.85 | NQO1 (0.34) | ALDH1A1KCNJ5KCNJ3 | |
| SCHEMBL9025443 | 0.84 | NQO2 (0.37) | — | |
| SCHEMBL9024639 | 0.83 | NQO2 (0.42) | — | |
| SCHEMBL9023982 | 0.79 | MAPT (0.36) | — | |
| SCHEMBL9023958 | 0.77 | TOP2A (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0347749-A2 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |