Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 8/20 | 0.36 |
| ▸ | NQO1 | P15559 | 7/20 | 0.36 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023942 | 0.95 | NQO1 (0.35) | NQO2NQO1TOP2A | |
| SCHEMBL9023350 | 0.95 | TOP2A (0.38) | NQO2NQO1KMT2ATOP2AALDH1A1 | |
| SCHEMBL9024021 | 0.94 | NQO1 (0.34) | NQO2NQO1KCNJ5KCNJ3TOP2A | |
| SCHEMBL9025443 | 0.93 | NQO2 (0.37) | NQO2NQO1TOP2A | |
| SCHEMBL9024639 | 0.93 | NQO2 (0.42) | NQO2NQO1 | |
| SCHEMBL9024967 | 0.88 | ALDH1A1 (0.31) | KCNJ5KCNJ3ALDH1A1 | |
| SCHEMBL9023958 | 0.87 | TOP2A (0.42) | NQO2NQO1KMT2ATOP2AALDH1A1 | |
| SCHEMBL9024018 | 0.85 | NQO2 (0.38) | NQO2NQO1KMT2ATOP2AALDH1A1 | |
| SCHEMBL9023509 | 0.85 | NQO2 (0.33) | NQO2NQO1 | |
| SCHEMBL9024437 | 0.84 | NQO2 (0.37) | NQO2NQO1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0347749-A2 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |