Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 14/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 14/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9589928 | 0.91 | AGTR1 (0.55) | AGTR1AGTR2PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL9588802 | 0.86 | AGTR1 (0.62) | AGTR1AGTR2PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL9025413 | 0.81 | AGTR1 (0.61) | AGTR1AGTR2PDE4APDE4BPDE4C | |
| SCHEMBL9598462 | 0.80 | AGTR1 (0.60) | AGTR1AGTR2PDE4APDE4BPDE4C | |
| SCHEMBL9591968 | 0.78 | AGTR1 (0.56) | AGTR1AGTR2PDE4APDE4BPDE4C | |
| SCHEMBL9589857 | 0.76 | AGTR1 (0.62) | AGTR1AGTR2PDE4APDE4BPDE4C | |
| SCHEMBL9590473 | 0.76 | AGTR1 (0.62) | AGTR1AGTR2PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL9591558 | 0.76 | AGTR1 (0.75) | AGTR1AGTR2PDE4APDE4BPDE4C | |
| SCHEMBL9590913 | 0.75 | AGTR1 (0.61) | AGTR1AGTR2PDE4APDE4BPDE4C | |
| SCHEMBL9372818 | 0.74 | PDE4A (0.38) | AGTR1AGTR2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611368-B1 | SUBSTITUTED AMINOPYRIMIDINES AS ANGIOTENSIN II ANTAGONISTS | AMERICAN HOME PROD (US) | 1996-02-07 | — | — | EP | disclosed |