Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.42 |
| ▸ | XIAP | P98170 | 7/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 7/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9108112 | 0.93 | GHSR (0.47) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL9108111 | 0.93 | GHSR (0.47) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL9119823 | 0.93 | GHSR (0.41) | GHSRXIAPAGTR1NPY1RSCN9A | |
| SCHEMBL9120215 | 0.92 | GHSR (0.41) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL9105594 | 0.86 | GHSR (0.47) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL9105597 | 0.86 | GHSR (0.47) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL9108993 | 0.86 | GHSR (0.46) | GHSRXIAPAGTR1SCN9A | |
| SCHEMBL9108181 | 0.86 | GHSR (0.60) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL9108986 | 0.86 | GHSR (0.46) | GHSRXIAPAGTR1SCN9A | |
| SCHEMBL9105901 | 0.85 | GHSR (0.54) | GHSRXIAPAGTR1NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711287-A4 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO INC (US) | 1996-08-28 | — | — | EP | disclosed |
| EP-0711287-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO. INC. (US) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995003290-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-02-02 | — | — | WO | disclosed |