Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025810 | 0.92 | BTK (0.36) | MAPK1HRH3CHRM2CHRM1CHRM3 | |
| SCHEMBL9032134 | 0.87 | ALDH1A1 (0.42) | ALDH1A1KMT2AHPGDGAARECQL | |
| SCHEMBL9032127 | 0.87 | ALDH1A1 (0.42) | ALDH1A1KMT2AHPGDGAARECQL | |
| SCHEMBL9032138 | 0.87 | ALDH1A1 (0.42) | ALDH1A1KMT2AHPGDGAARECQL | |
| SCHEMBL9032136 | 0.87 | ALDH1A1 (0.42) | ALDH1A1KMT2AHPGDGAARECQL | |
| SCHEMBL9031661 | 0.83 | NR1H2 (0.34) | MAPK1HRH3CHRM2CHRM1CHRM3 | |
| SCHEMBL9031664 | 0.83 | NR1H2 (0.34) | MAPK1HRH3CHRM2CHRM1CHRM3 | |
| SCHEMBL9033676 | 0.83 | NR1H2 (0.34) | MAPK1HRH3CHRM2CHRM1CHRM3 | |
| SCHEMBL9031668 | 0.83 | NR1H2 (0.34) | MAPK1HRH3CHRM2CHRM1CHRM3 | |
| SCHEMBL9034069 | 0.82 | ALDH1A1 (0.33) | MAPK1HRH3ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719774-A1 | A method for production of dibenzoxazolyl thiophenes | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5310940-A | Sulfiding, cyclization | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5221749-A | Reacting a thiophene,2,5-dicarboxylic acid diester with a 2-aminophenol in the presence of an acid catalyst | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1993-06-22 | — | — | US | disclosed |
| US-5093504-A | PRODUCTION OF THIOPHENE-2,5-DICARBOXYLIC ACID DIESTERS, TETRAHYDROTHIOPHENE-2,5-DICARBOXYLIC ACID DIESTERS AND DIBENZOXAZOLYLTHIOPHENES | SUMITOMO SEIKA CHEMICALS, CO., LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0387725-A2 | Production of thiophene-2,5-dicarboxylic acid diesters and tetrahydrothiophene-2,5-dicarboxylic acid diesters | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1990-09-19 | — | — | EP | disclosed |