Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026158 | 0.85 | KDM4C (0.36) | KDM4CDHFRNPC1RAB9AALDH1A1 | |
| SCHEMBL9026594 | 0.84 | KDM4C (0.35) | KDM4CDHFRNPC1RAB9AALDH1A1 | |
| SCHEMBL9026362 | 0.83 | KDM4C (0.35) | KDM4CNPC1RAB9AHTR2CSLC6A4 | |
| SCHEMBL17150203 | 0.76 | KDM4C (0.42) | KDM4CNPC1RAB9ATSHRMAPK1 | |
| SCHEMBL4184332 | 0.76 | KDM4C (0.47) | KDM4CMEN1KMT2APSEN1PSEN2 | |
| SCHEMBL11258174 | 0.75 | KDM4C (0.46) | KDM4CALDH1A1MEN1KMT2AEP300 | |
| SCHEMBL7445879 | 0.72 | TACR1 (0.47) | KDM4CALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1563233 | 0.72 | KDM4C (0.40) | KDM4CDHFRNPC1RAB9AALDH1A1 | |
| SCHEMBL16815740 | 0.71 | KDM4C (0.46) | KDM4CDHFRNPC1RAB9AALDH1A1 | |
| SCHEMBL1564255 | 0.71 | KDM4C (0.39) | KDM4CDHFRSLC6A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411150-B1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMA CO LTD (JP) | 1996-11-27 | — | — | EP | disclosed |