Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16923117 | 0.78 | CYP3A4 (0.54) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| SCHEMBL11461 | 0.68 | CYP3A4 (0.45) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| SCHEMBL11374120 | 0.68 | PDE5A (0.40) | CYP3A4LMNAMAPTMEN1KMT2A | |
| SCHEMBL29154249 | 0.67 | CYP3A4 (0.59) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| SCHEMBL31241182 | 0.65 | MAPT (0.61) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| SCHEMBL28581728 | 0.65 | MAPT (0.61) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| SCHEMBL24220264 | 0.65 | NOTUM (0.48) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| SCHEMBL9025866 | 0.64 | LMNA (0.67) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| SCHEMBL2532397 | 0.64 | LMNA (0.78) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| SCHEMBL16673120 | 0.64 | CYP3A4 (0.62) | CYP3A4LMNAMAPTENPP2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6073165-A | — | — | None | — | — | JP | disclosed |
| EP-0576393-B1 | Curable compositions based on epoxy resins or mixtures of epoxy resins and polyisocyanates containing a trisimidazolyltriazone | CIBA GEIGY AG (CH) | 1996-04-10 | — | — | EP | disclosed |
| US-5391681-A | Hardeners or promoters having low temperature reactivity and storage stability | CIBA-GEIGY CORPORATION (US) | 1995-02-21 | — | — | US | disclosed |
| JP-H0673165-A | CURABLE COMPOSITION BASED ON EPOXY RESIN OR MIXTURE OF EPOXY RESIN AND POLYISOCYANATE CONTAINING TRISIMIDAZOLYL TRIAZINE | CIBA GEIGY AG | 1994-03-15 | — | — | JP | disclosed |
| EP-0576393-A1 | Curable compositions based on epoxy resins or mixtures of epoxy resins and polyisocyanates containing a trisimidazolyltriazone | CIBA-GEIGY AG (CH) | 1993-12-29 | — | — | EP | disclosed |