Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 5/20 | 0.60 |
| ▸ | NPY1R | P25929 | 3/20 | 0.58 |
| ▸ | GHSR | Q92847 | 4/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9039183 | 0.92 | GHSR (0.52) | XIAPNPY1RGHSRAGTR1SCN9A | |
| SCHEMBL8329256 | 0.91 | GHSR (0.57) | XIAPNPY1RGHSRAGTR1SCN9A | |
| SCHEMBL7791594 | 0.91 | GHSR (0.58) | XIAPNPY1RGHSRAGTR1SCN9A | |
| SCHEMBL7785915 | 0.90 | GHSR (0.56) | XIAPNPY1RGHSRAGTR1SCN9A | |
| SCHEMBL9025795 | 0.89 | GHSR (0.57) | XIAPNPY1RGHSRAGTR1SCN9A | |
| SCHEMBL9025790 | 0.89 | GHSR (0.57) | XIAPNPY1RGHSRAGTR1SCN9A | |
| SCHEMBL7792865 | 0.89 | GHSR (0.55) | XIAPNPY1RGHSRAGTR1SCN9A | |
| SCHEMBL9090302 | 0.89 | GHSR (0.55) | XIAPNPY1RGHSRAGTR1SCN9A | |
| SCHEMBL7794013 | 0.89 | GHSR (0.55) | XIAPNPY1RGHSRAGTR1SCN9A | |
| SCHEMBL7791688 | 0.89 | GHSR (0.56) | XIAPNPY1RGHSRAGTR1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513974-B1 | Novel benzo-fused lactams that promote the release of growth hormone | MERCK & CO INC (US) | 1996-09-04 | — | — | EP | disclosed |
| US-5310737-A | Benzo-fused lactams that promote the release of growth hormone | MERCK & CO., INC. (US) | 1994-05-10 | — | — | US | disclosed |
| US-5206235-A | Animal growth regulators; stimulants | MERCK & CO., INC. (US) | 1993-04-27 | — | — | US | disclosed |
| EP-0513974-A1 | Novel benzo-fused lactams that promote the release of growth hormone | MERCK & CO. INC. (US) | 1992-11-19 | — | — | EP | disclosed |
| WO-1992016524-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1992-10-01 | — | — | WO | disclosed |