SCHEMBL9026306

SCHEMBL9026306

c1c[nH]c(-c2nnnc(-c3ncc[nH]3)c2-c2ncc[nH]2)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 2/20 0.42
MTOR P42345 1/20 0.42
ADK P55263 1/20 0.42
ALDH1A1 P00352 4/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 2/20 0.35
PDE4A P27815 1/20 0.35
PDE4B Q07343 1/20 0.35
PDE4C Q08493 1/20 0.35
PDE4D Q08499 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
ADORA2A P29274 2/20 0.33
ADORA1 P30542 2/20 0.33
SMPD3 Q9NY59 1/20 0.33
IDO1 P14902 1/20 0.33
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4554719 0.76 NISCH (0.37) NISCHMTORADKALDH1A1MEN1
SCHEMBL81650 0.72 NISCH (0.59) NISCHMTORADKALDH1A1MEN1
SCHEMBL28425230 0.70 NISCH (0.56) NISCHMTORADKALDH1A1MEN1
Hydrochloric Acid SCHEMBL1536214 0.70 NISCH (0.56) NISCHMTORADKALDH1A1MEN1
SCHEMBL13977589 0.69 NISCH (0.50) NISCHMTORADKALDH1A1MEN1
SCHEMBL11462 0.68 NISCH (0.45) NISCHMTORADKALDH1A1MEN1
SCHEMBL30216772 0.65 NISCH (0.52) NISCHMTORADKALDH1A1MEN1
SCHEMBL28581729 0.65 NISCH (0.52) NISCHMTORADKALDH1A1MEN1
SCHEMBL1472570 0.65 NISCH (0.42) NISCHMTORADKALDH1A1MEN1
SCHEMBL28382846 0.65 CSNK1A1 (0.56) NISCHMTORADKALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110790926-B Preparation method and application of palladium-containing metal-polycarbocarbene porous organic polymer 中南大学 2020-08-25 CN disclosed
CN-110790926-A Preparation method and application of palladium-containing metal-polycarbocarbene porous organic polymer 中南大学 2020-02-14 CN disclosed
EP-0576393-B1 Curable compositions based on epoxy resins or mixtures of epoxy resins and polyisocyanates containing a trisimidazolyltriazone CIBA GEIGY AG (CH) 1996-04-10 EP disclosed
EP-0576393-A1 Curable compositions based on epoxy resins or mixtures of epoxy resins and polyisocyanates containing a trisimidazolyltriazone CIBA-GEIGY AG (CH) 1993-12-29 EP disclosed