Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.59 |
| ▸ | HTR2A | P28223 | 4/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027042 | 0.89 | HRH3 (0.56) | HRH3HTR2AHTR2CDRD2CHRNA7 | |
| SCHEMBL9027181 | 0.87 | KDM4E (0.43) | HRH3HTR2ADRD2CHRNA7BCHE | |
| SCHEMBL9027275 | 0.84 | HRH3 (0.67) | HRH3DRD2CHRNA7HRH4KDM4E | |
| SCHEMBL9223276 | 0.83 | HRH3 (0.67) | HRH3HTR2AHTR2CDRD2CHRNA7 | |
| SCHEMBL9027269 | 0.82 | HRH3 (0.65) | HRH3HTR2AHTR2CDRD2CHRNA7 | |
| SCHEMBL9027015 | 0.82 | HRH3 (0.39) | HRH3HTR2CCHRNA7BCHEHRH4 | |
| SCHEMBL9026157 | 0.81 | HRH3 (0.64) | HRH3HTR2AHTR2CDRD2CHRNA7 | |
| SCHEMBL9027094 | 0.81 | HRH3 (0.64) | HRH3HTR2AHTR2CDRD2CHRNA7 | |
| SCHEMBL9027107 | 0.79 | HRH3 (0.66) | HRH3DRD2CHRNA7BCHEHRH4 | |
| SCHEMBL9026162 | 0.77 | HRH3 (0.63) | HRH3DRD2CHRNA7BCHEHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537532-B1 | 2,2'-Alkylenediindole derivatives, process for their production, medicines containing them and their use as anti-ulcer agents | NISSHIN FLOUR MILLING CO (JP) | 1996-11-27 | — | — | EP | disclosed |
| US-5326879-A | Indole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0537532-A1 | 2,2'-Alkylenediindole derivatives, process for their production, medicines containing them and their use as anti-ulcer agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-04-21 | — | — | EP | disclosed |